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Abstract

The aim of this work was to determine the occurrence of calcification in the aortic artery of cows at different ages in Wasit Governorate. The aortic tissue of hearts from healthy cows at the ages of 1, 2, 3 and 4 years was collected. Histological sections from these samples were prepared and stained with Hematoxylin and Eosin and alizarin red, Von Kossa, to determine the deposition of calcium salts. In the 1-year-old group, the wall of the aorta includes the intima, containing one layer of endothelium cells next to the arterial lumen, media with elastic fiber, and adventitia made from connective tissue. Calcium salts at this age had been deposited in tunica media in the form of small white granules. The aortic artery of 2 years group showed the presence of calcium salts as large brown spots in the media layer. Calcification in the aorta of cows at the age of 3 years was larger as large brown clusters. At the age 4 years, calcium salts scattered widely in the middle layer. The results revealed that the calcification increases with the aging animals.

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Cow Von Kossa Aorta Calcification

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The authors transfer the copyrights of their papers to the Iranian Society of Ichthyology. However, the information could be used in accordance with the Creative Commons licence (Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

How to Cite
AL-SALMAN, A. A.-J., ZEGYER, E. A. K., & AL-IEDANI, H. S. (2023). Study of aortic calcification in cows examined in Wasit Governorate, Iraq. Iranian Journal of Ichthyology, 10(Special Issue 1), 14–21. Retrieved from https://ijichthyol.org/index.php/iji/article/view/890
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References

  1. Bernacca G.M.; Fisher, A.C.; Wilkinson, R.; Mackay, T.G. & Wheatley, D.J. 1992. Calcification and stress distribution in bovine pericardial heart valves. Journal of Biomedical Materials Research 26: 959-966.
  2. Demer, L.L. & Tintut, Y. 2008. Vascular calcification: pathobiology of a multifaceted disease. Circulation. 117: 2938-2948.
  3. Fletcher, O. & Abdul-Aziz, T. 2008. Cardiovascular system. Avian histopathology. Madison, USA: American Association of Avian Pathologists, Inc. pp: 98-129.
  4. Guyton, A.C. & Hall, E. 2006. Textbook of Medical Physiology. Elsevier lnc.170 p.
  5. Herzog, H. 2010. Some we love, some we hate, some we eat: Why it’s sohard to think straight about animals. New York, NY: Harper: pp. 237-263.
  6. Hofmann, J.J.; Briot, A.; Enciso, J.; Zovein, A.C.; Ren, S.; Zhang, Z.W.; Radtke, F.; Simons, M.; Wang, Y. & Iruela-Arispe, M.L. 2012. Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome. Development 139: 4449-4460.
  7. Josian, M.M.; Antononio, M.O.; Carlos, R.P.; Selma, M.M. & Maria, L.E. 2004. Structure of the aortic wall in the guinea pig and rat. Brazilian Journal of Morphological Sciences 21(1): 35-38.
  8. Levick, J.R. 1991. An introduction to cardiovascular physiology, Arnold: pp.1-122.
  9. Miller, J.D. 2013. Cardiovascular calcification: Orbicular origins. Nature Materials 12: 476-478.
  10. Otto, C.M. 2008. Calcific aortic stenosis: time to look more closely at the valve. The New England Journal of Medicine 359: 1395-1398.
  11. Raggi, P.; Callister, T.Q.; Cooil, B.; He, Z.X.; Lippolis, N.J.; Russo, D.J.; Alan Z. & John J.M. 2000. Identification of patients at increased risk of first unheralded acute myocardial infarction by electron-beam computed tomography. Circulation 101(8): 850-855.
  12. Roberts, W.C. 1986. The senile cardiac calcification syndrome. The American Journal of Cardiology 58(6): 572-4.
  13. Schoen, F.J.; Hirsch, D.; Bianco, R.W. & Levy, R.J. 1994. Onset and progression of calcification in porcine aortic bioprosthetic valves implanted as orthotopic mitral valve replacements in juvenile sheep. The Journal of Thoracic and Cardiovascular Surgery 108: 880-887.
  14. Schoen, F.J. & Levy, R.J. 1999. Tissue Heart Valves: Current Challenges and Future Research Perspectives. Journal of Biomedical Materials Research 47: 439-465.
  15. Schurgers. J. 2012. Vascular calcification: The price to pay for anticoagulation therapy with vitamin K- antagonists. Blood Reviews 26(4): 155-166.
  16. Simmons, C.A.; Grant, G.R.; Manduchi, E. & Davies, P.F. 2005. Spatial Heterogeneity of Endothelial Phenotypes Correlates With Side Specific Vulnerability to Calcification in Normal Porcine Aortic Valves. Circulation Research 96: 792-799.
  17. Tolosa, E.M.C.; Rodrigues, C.J.; Behemer, A.O. & Freitas-Neto, A.G. 2003. Manual de Técnicas para Histologia Normal e Patológica. Manole, São Paulo.
  18. Towler, D.A. 2008. Vascular calcification: a perspective on an imminent disease epidemic. IBMS BoneKey 5: 41-58.
  19. Weiss, R.M.; Ohashi, M.; Miller, J.D.; Young, S.G. & Heistad, D.D. 2006. Calcific Aortic Valve Stenosis in Old Hypercholesterolemic Mice. Journal of Circulation112: 2065-2069.
  20. Wilson, P.W.; Kauppila, L.I.; O’Donnell, C.J.; Kiel, D.P.; Hannan, M.; Polak, J.M. & Cupples, L.A. 2001. Abdominal aortic calcific deposits are an important predictor of vascular morbidity and mortality. Circulation 103(11): 1529.