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Abstract

The sub-lethal toxicity of Chlorpyrifos on selected oxidative stress biomarkers (malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione S-transferase (GST), and reduced glutathione (GSH)) and acetylcholinesterase (AChE) activity was examined in the olfactory organ of Labeo bata under sub-lethal exposures. Chlorpyrifos (CPF) was administered at predetermined exposure concentrations (21.93 and 36.54µg/L) and monitored on days 15 and 30 of the experimental periods. The experimental groups showed significantly higher values (P<0.05) of MDA, SOD, CAT, GST and GPx in CPF exposed fish compared to control. AChE and GSH were significantly lower in exposed fish. In general, biomarker depictions indicate that CPF exposures are capable of inducing stress-specific effects at the biochemical and physiological levels negatively impacting the overall health and longevity of such animals.

Keywords

Sub-lethal toxicity Chlorpyrifos oxidative stress biomarkers Labeo bata

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The authors transfer the copyrights of their papers to the Iranian Society of Ichthyology. However, the information could be used in accordance with the Creative Commons licence (Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

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SAMAJDAR, I., SAHA, S., & MANDAL, D. K. (2024). Chlorpyrifos induced oxidative stress responses and alteration of acetylcholinesterase activity in the olfactory organ of freshwater minor carp, <i>Labeo bata</i>. Iranian Journal of Ichthyology, 10(4), 248–263. https://doi.org/10.22034/iji.v10i4.998
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